Engineer in Cell Biology (M/F)

Reference : ERIN-2018-031

Type: Engineer
Contract type: Fixed term contract
Duration: 24 months
Place: Belvaux

Context

 

The Luxembourg Institute of Science and Technology (LIST) is offering a full time engineer in cell biology. The engineer will be part of the Department of Environmental Research and Innovation (ERIN) at LIST. With a team of more than 170 scientists and engineers from life science, environmental science, and IT science, the ERIN department has the necessary interdisciplinary knowledge and skills to tackle major environmental challenges our society is facing today: climate change mitigation, ecosystem resilience, sustainable energy systems, efficient use of renewable resources, environmental pollution prevention and control.

She/he will join more specifically the Environmental Health Group. The Environmental Health Group develops complex 3D - in vitro models for toxicological testing as a major research activity. Such models undergo in house validation under laboratory conditions and are applied to a wide range of contaminants from chemicals to nanomaterials. These models are then applied within nationally and internationally funded research projects and in collaborative research projects with industry.

The applicant will work in the framework of projects aiming at further development, pre-validation and application of new in vitro models for lung toxicity, which are currently lacking models in the field of alternative methods. The projects are designed to help bridge the technical and funding gap between research-driven discoveries and their commercialisation/utilisation, thereby enhancing the impact of Luxembourg’s research on economy and society.

 

Description

 

The applicant’s main tasks will be related to recently funded projects in which a set of assays will be applied and further developed along the TRL scale with the final aim to commercialise these assays.

She/he will mainly be asked to:

  • Ensure the maintenance of the various cell lines;
  • Assemble 3D inserts for exposure experiments;
  • Perform 3D in vitro exposure experiments;
  • Sample preparation of biological samples;
  • Analyse samples (biochemical, molecular biological methods);
  • Actively engage in the further development of existing in vitro models;
  • Actively propose potential improvements and test for their added value.

The applicant might also be asked to intervene on the following tasks:

  • Contribute to RDI projects/work packages in a support scope
  • Follow-up of equipment (preparation, calibration and upgrading of materials)

 


Profile

 

Education

  • The candidate has preferably a diploma corresponding to a MSc in biology, cell biology or a related field

Required seniority

  • It is expected that the candidate has experience with cell-culture and is able to use the relevant equipment present within the ERIN Department: e.g. cell culture, microscopes, the various exposure systems for cell exposure, ELISA, DNA/RNA extraction, real-time PCR plus to use a FACS

Competences

The candidate should have relevant expertise in:

  • Knowledge about the state-of-the-art of 3D cell culture;
  • Cell biology; knowledge in 3D cell culture will be an asset;
  • Analysis of relevant endpoints for in vitro toxicity studies;
  • Reporting of experimental data;
  • Define adaptations and further improvements of the model;
  • Participate in the definition of SOPs.

Language

  • The candidate must be able to communicate in English
  • Knowledge of French or German is an asset

 

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Contact

GUTLEB_Arno_2018_www.jpg
Dr Arno GUTLEB
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Carmine ALIBERTI