PhD position in high-resolution chemical imaging for nano-toxicological studies

Reference : MRT-2019-027

Type: PhD Student
Contract type: Fixed term contract
Duration: 14 months (+ 22 months + potentially 12 months extension)
Place: Belvaux

Context

 

As a key player in research and innovation in Luxembourg, the Luxembourg Institute of Science and Technology (LIST), with its employees, is active in the domains of materials, the environment and IT. As an RTO (Research and Technology Organisation) and with its interdisciplinary impact-driven approach, LIST contributes to the development of Luxembourg’s economy and society.
The Materials Research and Technology Department (MRT) translates cutting-edge materials research into applicable technology, with about 150 collaborators. For this, the department cultivates close relationships and joint projects with both academic and industrial partners, and contributes to Luxembourg's and Europe's innovation agenda in Materials Research and Technology.

The Advanced Instrumentation for Ion Nano-Analytics (AINA) group of the MRT department at the LIST is renowned for developing innovative nano-analytical techniques for materials characterization and life science applications. During the past few years, we have been developing in particular a Secondary Ion Mass Spectrometry (SIMS) add-on system for the Helium Ion Microscope (HIM) and for a Transmission Electron Microscope (TEM), allowing the advantages of high spatial resolution and high sensitivity chemical information to be combined. The research activities of the AINA group cover fundamentals, instrument development and applications.

 

Description

 

We are currently looking for a well-motivated candidate to perform PhD research to participate in a collaborative project exploring the effects of oral exposure and gut-targeted toxicity of emerging environmental pollutant perfluorinated carboxylic acid (PFCA). The project offers opportunities to use cutting-edge Correlative Microscopy based on Mass Spectrometry such as Electron Microscopy and Secondary Ion Mass Spectrometry (SIMS) to combine multidimensional information from complementary techniques. Thus, it bridges the various spatial-resolution gaps and enables the integration of structural information gathered from multiple levels of the biological hierarchy into one common framework. The candidate will acquire highly-valued skills in analysis and correlative microscopy and data interpretation and handling. The project is a close collaboration with INRA (Toulouse, France) and the University of Pau (France).

 


Profile

 

Education

  • Master's degree in Materials Science or Biology, or closely related fields

Competencies

  • Master diploma with a university education focusing on biology, biochemistry, chemistry, materials science or similar
  • Interest in microscopy, mass spectrometry and toxicology
  • Self-motivated by passion for science and research
  • Ability to work in a team with team-spirit mandatory

Language

  • English (very good knowledge is mandatory)

 

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MRT-2019-027


 

Apply online

Contact

Dr Tom WIRTZ
Dr Tom WIRTZ

 Stéphanie LUCADELLO
Stéphanie LUCADELLO

Linked files

MRT-2019-027.pdf